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Abstract

Research in Medical & Engineering Sciences

MicroRNAs: Biomarkers or Therapeutic Targets?

  • Open or CloseAreti Moushi*

    Cyprus Institute of Neurology and Genetics, Cyprus

    *Corresponding author:Areti Moushi, Cyprus Institute of Neurology and Genetics, Cyprus

Submission: July 25, 2019;Published: August 27, 2019

DOI: 10.31031/RMES.2019.08.000681

ISSN: 2576-8816
Volume8 Issue2

Abstract

MicroRNAs are small non-coding RNAs of approximately 22 nucleotides, that control gene expression. They pair with s specific part on the untranslated region (UTR) of their target mRNAs and silence their expression, either by inhibiting their translation or by degrading the sequence. Therefore, a dysregulation in the expression of miRNAs results to the dysregulation of their target genes which in several cases they may play in different diseases. In the past decades the investigation of these non-coding RNAs has been comprehensive and thorough. MiRNAs have been investigated for their possible role as biomarkers as well as therapeutic targets.

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