Department of Pharmacology and Clinical Pharmacy, University of Tripoli, Libya
*Corresponding author: Fathi Mohamed Sherif, Department of Pharmacology, University of Tripoli, Libya
Submission: March 05, 2018; Published: March 29, 2018
ISSN : 2576-8816Volume4 Issue4
Preeclampsia is a disorder of uncertain etiology of human pregnancy. It defines by high blood pressure and high protein in urine. If it left without treatment, it will change to eclampsia which leads to high rates of morbidity and mortality . Its prevalence is beyond 10% and is the main maternal death. If preeclampsia occurs before 32 weeks of gestation, it is considered as earlyonset and is more likely of high morbidity rate. Preeclampsia is associated with multiple maternal and fetal adverse effects . Periodontal disease (PD) is a chronic infection of gingival with dental supportive structures caused by periopathogen bacteria. PD is identified by extensive damage to dental supportive structures as alveolar bone accompanied by forming pocket and gingival recession. This involves of direct tissue damage as a result of bacterial plaque and of indirect by bacterial effects on the immune system . Inflammation and infection play a role in the pathogenesis of preterm birth through various path physiological mechanisms. It occurs in 15% of women and is more in pregnancy which specified by clinical attachment loss. PD is either gingivitis or periodontitis. Interestingly, published data have indicated that preeclampsia cases have significantly higher attachment loss and gingival recession than control cases [4,5].