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Abstract

Research in Medical & Engineering Sciences

Role of Mesenchymal Stem Cells (MSC) in the Management of Brain Stroke

Submission: August 31, 2017; Published: September 19, 2017

DOI: 10.31031/RMES.2017.01.000516

ISSN: 2576-8816
Volume1 Issue4

Abstract

Cerebro vascular Accident (CVA) also commonly known as brain stroke leads to death of brain cells. There are limitations in the effective management of stroke due to lack of definitive treatment measures. In selective cases, interventional radiological and surgical procedure may reduce or prevent the progression of disease. Medical management mainly aimed at long term prevention of stroke. There are no proven medical or surgical measures to rescue the damaged neurons of CNS origin. Mesenchymal stem cells (MSCs) have emerged as a promising approach for the replacement of lost neurons by multiple unique properties of MSCs like neo angiogenesis, stimulating endogenous neurogenesis, autocrine effect, migration, inflammatory milieu and reducing glial scar formation. MSCs are heterogeneous cells with fibroblast-like nature. They can be isolated from nearly all human tissues, including, but not limited to, placenta, umbilical cord, adipose tissue, bone marrow, skeletal muscle and heart. In this mini review, we summarize importance of Mesenchymal stem cells in the Management of Brain Stroke.

Keywords: Brain stroke; Cerebro vascular accident; Mesenchymal stem cells

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