Abstract

Studies on molecular interactions using ultrasonic and spectroscopic technique in ternary liquid mixture of drug ciprofloxacin, a proteinogenic amino acid l-glutamic acid in aqueous medium has been carried out at 300.15K and 2MHz frequency. Different acoustical parameters such as adiabatic compressibility (β), intermolecular free length (Lf), acoustic impedance (z) etc are evaluated using experimental values of density (ρ) and ultrasonic velocity (U) These parameters along with UV-Visible spectroscopic evidences demonstrates drug-amino acid molecular interaction existing in the aqueous media.

Keywords: Ciprofloxacin; L-glutamic acid; Adiabatic compressibility; Intermolecular free length; Acoustic impedance