Abstract

Objectives: Cigarette smoking is associated with subfertility in males and may lead to a decrease in sperm concentration, lower sperm motility, and a reduced percentage of morphologically normal sperms. The objective of the study is to find out the effect of smoking with semen parameters and the relationship between amount of cigarette smoking and semen parameters.

Method: This is a hospital-based cohort study conducted in the Infertility clinics of NEIGRIHMS from December 2019 for a period of 1year. 254 male partners were enrolled for the study. Routine semen analysis was carried out under light microscopy according to WHO guidelines.2010. Data was analysed to find out relation of smoking with semen parameters and the relationship between amount of cigarette smoking per day and semen parameters by using SPSS Software Version 21.

Result: In the one-year period we had 140 cases of non-smoker and 114 cases of smokers. On analysis of the findings of sperm count, smokers have relative risk of 2.45 of getting oligozoospermia (p value=0.0005). Smokers have relative risk of 1.5 of having total motility <50%. For progressive motility, smokers have relative risk of 2.01 of getting progressive motility<32%. No dose relationship with abnormal semen parameter.

Conclusion: Smoking affected sperm count, and total and progressive motility but there was no dose and effect relationship between number of cigarettes per day and its affect on semen parameter.

Keywords: Smoking; Non-smokers; Total motility; Progressive motility; Vitality; Morphology