Abstract

Orthoplastic Surgery & Orthopedic Care International Journal

A Systematic Review of Beneficial Outcomes of Omega-3 Fatty Acid in Human Musculoskeletal Diseases

Submission: May 05, 2022; Published: June 10, 2022

DOI: 10.31031/OOIJ.2022.02.000546

ISSN: 2578-0069
Volume2 Issue5

Abstract

Omega 3 fatty acid are long chain polyunsaturated fatty acid found mostly in marine & Plant sources Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) are the classes of omega 3 fatty acid that are mostly derived from marine sources, whereas another class of omega 3 fatty acid i.e., Linolenic acid is mostly found in plant sources. Consumption of EPA & DHA daily approx. 3-4gm will help in lowering serum triglycerides level by 25-30%, and in subjects suffering from hypertriglyceridemia, there serum triglycerides level will be lowered approximately 50%. Essential fatty acid for human beings are Alpha-Linoleic Acid (ALA, omega-3) and Linoleic Acid (LA, omega-6) as they are not synthesized by human body, so they are consumed by them from exogeneous sources, for healthy brain higher amount of omega 3 must be include in our diet, for maintaining proper brain functioning specially in those having low baseline levels, and pregnant and lactating mothers and neuropsychiatric subjects need omega 3 fatty acid in sufficient quantity. Supplementation with omega 3 fatty acid helps to get rid from dementia, it’s having good antioxidant properties as well due to its anti-inflammatory action it proves to be best therapy for cardiovascular diseases.

Keywords: Omega 3 fatty acid; Linoleic acid; Salvia hispanica; Stearidonic acid

Abbreviations:EPA: Eicosapentaenoic Acid; DHA: Docosahexaenoic Acid; LA: Linoleic Acid; ALA: Alpha- Linoleic Acid; CHD: Coronary Heart Disease; BCC: Basal Cell Carcinoma; SCC: Squamous Cell Carcinoma; TLR4: Toll-Like Receptor 4; FFQ: Food Frequency Questionnaire; PPAR: Peroxisome Proliferators-Activated Receptor

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