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Abstract
Open Journal of Cardiology & Heart Diseases
Monitoring Cardiovascular Disease Progression
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Open or CloseJay N Cohn* and Mahfouz El Shahawy
University of Minnesota Medical School and Sarasota Memorial Hospital, USA
*Corresponding author:Cohn JN, University of Minnesota Medical School and Sarasota Memorial Hospital, USA
Submission: August 19, 2019 ;Published: August 28, 2019
ISSN: 2578-0204Volume3 Issue1
Abbreviations
Cardiovascular disease management guidelines and therapeutic trials are traditionally driven by efforts to reduce morbid events over a finite period of time, often the 10-year outcome that forms the basis for most algorithms aimed at defining risk [1,2]. This relatively short interval in a person’s life mandates that trials focus on advanced disease with high shortterm morbidity that will make it possible to identify a favorable effect of an intervention. This restriction makes it impractical to study early disease, when an intervention might be dramatically effective in prolonging life but will have too few morbid events over 5 or 10-year period of time to demonstrate effectiveness of therapy.
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