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Abstract

Open Access Research in Anatomy

CRISPR Applications Versus the Ethical and Regulatory Concerns

  • Open or Close Ahmed T M Elshennawy*

    Department of Anatomy, Faculty of Medicine, Al-Baha University, Saudi Arabia/p>

    *Corresponding author: Ahmed T M Elshennawy, Department of Anatomy, Faculty of Medicine, Al-Baha University, Saudi Arabia

Submission: December 12, 2020; Published: January 28, 2021

DOI: 10.31031/OARA.2021.02.000540

ISSN: 2577-1922
Volume2 Issue3

Abstract

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) has many applications such as editing the human genome and CRISPR-edited crops as well as CRISPRedited animals for the use of human organ transplants [1-4]. However, are the applications of CRISPR ethically defensible or not? For simplification, I will go through one example, the CRISPR-edited animals for the use of human organ transplants, where CRISPR-gene editing solves the problem occurring with the traditional use of PSCs (Pluripotent Stem Cells) or iPSCs (Induced Pluripotent Stem Cells) to produce differentiated β-cells of pancreatic islets of Langerhans to treat type 1 diabetes and the subsequent fatigue of these transplanted stem cells and failure to produce insulin and recurrence of diabetes again.

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