Abstract

Objective: To examine the prevalence of serum Vitamin D [Vit.D] insufficiency/deficiency in children/ adolescents with ADHD in Roanoke City of the Appalachian region of Virginia.

Methods: The levels of Vit.D in the serum of 35 children/adolescents [with the diagnosis of ADHD [with or without comorbidities] were examined and divided into three groups: Cohort A [deficient levels of Vit.D (≤20ng/L)]; Cohort B [insufficient levels of Vit.D (21-29ng/L)] and Cohort C [sufficient levels of Vit.D (≥30ng/)].

Result: There was a significant (P≤1.06E-06) difference in serum Vit.D in Cohort A vs Cohort B. Additionally, the levels of Vit.D in Cohort A was significantly lower (P≤1.78E-09) when compared to ‘normal/required’ levels of Vit.D. Similarly, the levels of Vit.D was significantly lower (P≤2.89E-07) in Cohort B vs Cohort C.

Conclusion: 85% of ADHD-affected children/adolescents in the Appalachian region exhibited insufficiency/deficient level of Vit.D

Keywords: ADHD; Appalachian region; Vitamin D