Abstract

Cancer serves as one of the main causes of death in global world, which has attracted tremendous attention due to high morbidities and mortalities. Currently, the traditional chemotherapies are still facing serious challenges, such as multidrug resistance, relapse and adverse events. What’s more, these risk factors will affect therapeutic efficacy. With the development of nanotechnologies, it provides great potential for cancer therapies ranging from non-targeting protein nanomaterials to nanobody with specific antigen recognition. In this mini review, we will mainly discuss the progress and approaches of protein nanomaterials being used to improve cancer therapeutic efficacy.

Keywords: Protein nanomaterials; Cancer therapies; Mitochondrial targeting; Nanobody