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Abstract
Modern Research in Dentistry
Relationship Between MRONJ (Medication
Related Osteonecrosis of the Jaw) and Endodontic
Theraphy
-
Open or ClosePicardo Silvana Noemi1*, Rodriguez Genta Sergio2, Basilaki Jorge Mario3,
Lopreite Gustavo Horacio4, Rey Eduardo5
1Head of Practical Works Chair in Oral and Maxillofacial Surgery II School of Dentistry
University of Buenos Aires and Department of Dentistry Favaloro Foundation University
Hospital, Argentina
2Head of Practical Works Chair in Oral and Maxillofacial Surgery II School of Dentistry,
University of Buenos Aires, Argentina
3Professor of Endodontics Kennedy University School of Dentistry, Former Associate professor
of endodontics at the Buenos Aires School of Dentistry, Licensed teacher of the School of
Dentistry of the University of Buenos Aires, Vocal Incoming President of the Sociedad De
Endodoncia, Argentina
4Associate Professor of Endodontics Kennedy University School of Dentistry, Former Associate
professor of endodontics at the Buenos Aires School of Dentistry, Licensed teacher of the
School of Dentistry of the University of Buenos Aires, Former President of the Sociedad De
Endodoncia, Argentina
5President of the National Academy of Dentistry, Consultant to the National Academy of
Medicine, Former Professor of Oral and Maxillofacial Surgery School of Dentistry, University
of Buenos Aires, Argentina
*Corresponding author:Picardo Silvana
Noemi, Head of Practical Works Chair in
Oral and Maxillofacial Surgery II School of
Dentistry University of Buenos Aires and
Department of Dentistry Favaloro Foundation
University Hospital
-
Open or ClosePicardo Silvana Noemi1*, Rodriguez Genta Sergio2, Basilaki Jorge Mario3,
Lopreite Gustavo Horacio4, Rey Eduardo5
1Head of Practical Works Chair in Oral and Maxillofacial Surgery II School of Dentistry University of Buenos Aires and Department of Dentistry Favaloro Foundation University Hospital, Argentina
2Head of Practical Works Chair in Oral and Maxillofacial Surgery II School of Dentistry, University of Buenos Aires, Argentina
3Professor of Endodontics Kennedy University School of Dentistry, Former Associate professor of endodontics at the Buenos Aires School of Dentistry, Licensed teacher of the School of Dentistry of the University of Buenos Aires, Vocal Incoming President of the Sociedad De Endodoncia, Argentina
4Associate Professor of Endodontics Kennedy University School of Dentistry, Former Associate professor of endodontics at the Buenos Aires School of Dentistry, Licensed teacher of the School of Dentistry of the University of Buenos Aires, Former President of the Sociedad De Endodoncia, Argentina
5President of the National Academy of Dentistry, Consultant to the National Academy of Medicine, Former Professor of Oral and Maxillofacial Surgery School of Dentistry, University of Buenos Aires, Argentina
*Corresponding author:Picardo Silvana Noemi, Head of Practical Works Chair in Oral and Maxillofacial Surgery II School of Dentistry University of Buenos Aires and Department of Dentistry Favaloro Foundation University Hospital
Submission: September 17, 2020 Published: September 29, 2020
ISSN:2637-7764Volume5 Issue4
Abstract
The American Surgery of Bone Mineral Research (ASBMR) in 2007 defined MRONJ as “necrotic bone area exposed to the oral environment with more than eight weeks of permanence, in the presence of chronic treatment with BPs, in the absence of radiation therapy to the head and neck”. In 2014 the American Association of Oral and Maxillofacial Surgeons (AAOMS) divided the MRONJ into 4 stages from 0 to 3, according to the clinical and radiological aspect of the osteonecrotic lesion:
A. stage 0: Osteonecrotic lesion without sign-pathognomonic evidence of osteonecrosis.
B. stage 1: osteonecrotic lesion with clinical signs and absence of clinical symptoms.
C. Stage 2: Osteonecrotic lesion with sign and evident clinical symptoms.
D. Stage 3: Osteonecrotic lesion with signs and evident symptoms that involve noble structures: pathological fractures, anesthesia of the lower dental nerve, oral-nasal communication, oral-sinus communication, skin fistulas. This article proposes explain relationship between MRONJ and endodontic therapy [1].
Keywords: Osteonecrotic lesion; Dental nerve; Oral-nasal; Endodontic; Bone accumulation; Pathology
Abbreviations: AR: Antiresorptive; BPs: Bisphosphonates; DS: Denosumab; AD: Antiangiogenic Drugs, MRONJ: Medication Related Osteonecrosis of the Jaw; ET: Endodontic Therapy
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