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Abstract

Modern Research in Dentistry

Periodontal Diagnosis: Shall Saliva and Gingival Crevicular Fluid Help the Clinician?
  • Open or CloseDiscepoli N1*, Mirra R1 and Marruganti C2

    1Department of Medical Biotechnologies, University of Siena, Italy

    2Undergraduate Program in Dentistry, University of Siena, Italy

    *Corresponding author:Discepoli Nicola, Department of Medical Biotechnologies, Unit of Periodontics, University of Siena, Siena, Italy

Submission: March 16, 2020 Published: May 07, 2020

DOI: 10.31031/MRD.2020.05.000604

ISSN:2637-7764
Volume5 Issue1

Abstract

Periodontal diseases are a group of inflammatory/infectious, multifactorial, diseases. The periodontal tissues house both microbial dysbiosis and host response dysregulation [1]. The most recent hypothesis about the pathogenesis of periodontal disease deals with the biological transition from a healthy periodontal tissue to a pathological one (characterized by inflammation and loss of clinical attachment). This transition is mediated by the dysregulation of the inflammatory response, caused by the presence of keystone pathogens. These bacteria (i.e. Porphyromonas gingivalis) differ from normal commensal bacteria: they are able to alter the inflammatory response even in minimal quantities [2,3].

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