Abstract

The ultrastructure of Submandibular gland [SMG] following low dose of Biochanin a [BCA] and 17beta estradiol [E2] application was observed. The pups were allocated randomly into control, BCA, E2, Dimethyl sulphoxide [DMSO] and euthanized at the 6^th, 14^th, 30^th, 60^th postnatal days [PND]. The SMG acinar and ductal structure, in addition to telocytes, were altered with the compounds of concern.

Keywords: Biochanin A; 17beta estradiol; Endocrinal disruptor

Abbreviations: BCA: Biochanin A; E2: 17beta estradiol; DMSO: Dimethylsulphoxide; SMG: Submandibular Salivary Gland; ED: Endocrinal Disruptor; TE: Transmission Electron Microscope; PND: Postnatal Day; gp: Group; M: Mitochondria; N: Nuclei; L: Lumen; rER: Rough Endoplasmic Reticulum; SG: Secretory Granules