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Innovation in Tissue Engineering & Regenerative Medicine

Radiotherapy for Wound Treated with BTM: A Case Report and Review of Literature

  • Open or CloseL Sun, S Cox and Ek Tan*

    Department of Plastic and Reconstructive Surgery, New Zealand

    *Corresponding author: EK Tan, Department of Plastic and Reconstructive Surgery, New Zealand

Submission: July 16, 2021; Published: September 15, 2021

DOI: 10.31031/ITERM.2021.01.000520

ISSN: 2578-0336
Volume1 Issue4


Biodegradable Temporizing Matrix (BTM) is a synthetic absorbable scaffold dressing that facilitates rapid growth of granulation tissue when laid on a vascular wound bed. Radiation is often known to hinder the regenerative potential of soft tissues due to early effects of the induction of apoptotic cell death and late effects of dysregulated collagen deposition due to damaged fibroblasts. There are no established results on the use of radiation following BTM integration and whether taken grafts layered on top of BTM are adversely affected or buffered from the damage of radiation due to the robust granulation layer underneath. Here, we present a case where a staged approach of BTM and split skin graft reconstruction have led to a cosmetically favorable result, without skin graft breakdown following adjuvant radiation.

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