Abstract

Ayurvedic fermentation as prescribed in classical texts is a versatile and powerful protocol for developing novel, traditional-like medicines. Ayurvedic medication, having a Prakriti (genetic) determinant, needs to be considered suitable for addressing metabolic disorders with immunologic implications, influenced by gut microbiome (as evidenced by the enterotypes). Obesity is a pathologic state on which the gut microbiota exercises influence in inflammatory and metabolic ways. When coupled with reverse pharmacology it would yield highly predictable results. It also bears potentials for redefining the protocol itself to deliver future products. In this article we essay on conceptualising the production and the prospect of developing new anti-obesity fermented nutraceutics/synbiotics to suit the prakriti of obese persons by prakriti-specific gut microbiome.

Keywords: Metabolic disorders; Immune system; Synbiotics; Ayurveda