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Gastroenterology Medicine & Research

Low Gastric Bicarbonate Secretions Seen in Cigarette Smokers

Submission: March 03, 2020; Published: March 09, 2020

DOI: 10.31031/GMR.2020.04.000590

ISSN 2637-7632
Volume4 Issue3


Sucralfate drug is well known for its miraculous effects on gastroduodenal mucosa and its therapeutic effects on peptic ulcer, but its mechanism of action is still a mystery. This drug administration of 3g daily for 4-6 weeks is an effective treatment on gastric bicarbonate secretion. Our observational study was focused on gastric bicarbonate secretion in 14 healthy smokers and 11 healthy age and sex-matched nonsmoker volunteers. The outcome of the study suggested that smokers produced low gastric bicarbonate secretions as compared to non-smokers.

Keywords:Low gastric bicarbonate; Cigarette smokers; Nicotine use; Gastric bicarb; Gastric secretions

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