Abstract

Objective: The neutrophil/lymphocyte ratio (NLR) is associated with atherosclerosis. In many prior studies, the relationship between prediabetes and cardiovascular disease (CVD) has been clearly established. In this study, we investigated the relationship between the NLR in prediabetic patients.

Method: Fifty-three consecutive patients without coronary artery disease who were diagnosed with prediabetes and 48 otherwise healthy subjects were enrolled in the study. Fasting blood glucose levels, HbA1c values and NLR were measured from venous blood samples.

Result: There were no statistical difference between the groups in terms of age, gender, body mass index. In the prediabetic group, the mean blood fasting glucose was 115±4mg/dl, whereas in the control group it was 90±5mg/dl. Mean HbA1c levels was % 5,9±0,4 in prediabetic group, whereas in the control group it was % 5,1±0,3. The NLR, was meaningfully higher in the prediabetic group than control group. Furthermore, there was a significantly positive correlation between the NLR in both the control group and prediabetic group.

Conclusion: In prediabetic group, NLR was detected higher than in healthy subjects.

Keywords: Neutrophil/lymphocyte ratio; Prediabetes