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Global Journal of Endocrinological Metabolism

Relationship between Neutrophil/Lymphocyte Ratio and Cardiometabolic Values in Patients with Prediabetes

  • Open or Close Isa Ardahanli1, Mehmet Celik2* and Mümtaz Takir3

    1 Department of Cardiology, Bilecik State Hospital, Turkey

    2 Department of Endocrinology and Metabolism, Bilecik State Hospital, Turkey

    3 Department of Endocrinology and Metabolism, Medeniyet University, Göztepe Training and Research

    *Corresponding author: Mehmet Celik, Department of Endocrinology and Metabolism, Bilecik State Hospital, Bilecik, Turkey

Submission: October 11, 2018; Published: October 24, 2018

DOI: 10.31031/GJEM.2018.02.000550

ISSN 2637-8019
Volume2 Issue4


Objective: The neutrophil/lymphocyte ratio (NLR) is associated with atherosclerosis. In many prior studies, the relationship between prediabetes and cardiovascular disease (CVD) has been clearly established. In this study, we investigated the relationship between the NLR in prediabetic patients.

Method: Fifty-three consecutive patients without coronary artery disease who were diagnosed with prediabetes and 48 otherwise healthy subjects were enrolled in the study. Fasting blood glucose levels, HbA1c values and NLR were measured from venous blood samples.

Result: There were no statistical difference between the groups in terms of age, gender, body mass index. In the prediabetic group, the mean blood fasting glucose was 115±4mg/dl, whereas in the control group it was 90±5mg/dl. Mean HbA1c levels was % 5,9±0,4 in prediabetic group, whereas in the control group it was % 5,1±0,3. The NLR, was meaningfully higher in the prediabetic group than control group. Furthermore, there was a significantly positive correlation between the NLR in both the control group and prediabetic group.

Conclusion: In prediabetic group, NLR was detected higher than in healthy subjects.

Keywords: Neutrophil/lymphocyte ratio; Prediabetes

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