Abstract

Cholesteatoma has the capacity for invasion, migration, change in differentiation, proliferation and recurrence which is quite similar to neo plasms; however, with no DNA affections, that rules out the hypothesis of being a neo plastic lesion [1,2]. Bone erosion is a fundamental biologic behavior of cholesteatoma that can cause serious complications. It is stimulated by a variety of factors that are still debated [3,4]. In the early 1962, the American Joint Committee [5] for Cancer Staging reported a standardized and widely accepted staging system for head and neck cancer. This allowed precise definition of the disease stage, planning treatment protocol and comparing outcome between different modalities and surgeons.