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Psychology and Psychotherapy: Research Study

Insights of Transdermal Drug Delivery: Prerequisites and Current Strategies

  • Open or CloseNiharika Lal*

    Department of Pharmacy, Metro Group of Institutions, India

    *Corresponding author: Niharika Lal, Department of Pharmacy, Metro Group of Institutions, Greater Noida, Uttar Pradesh, India

Submission: November 16, 2021;Published: December 10, 2021


Transdermal Drug Delivery System (TDDS) is an approachable substitute that could minimize as well as avoid limitations correlated with parental and oral drug delivery. The TDDS drug delivery system provides an acceptable and prolonged drug delivery in steady state and minimizes the possibility of peak associated side effects. For controlled drug delivery, utilization of transdermal patches is immensely userfriendly, comfortable and could be easily terminated if any kind of system toxicity arises. The transdermal route provides permeation of drug across the skin and into systemic circulation, avoiding the first pass hepatic metabolism of drugs which in turn increases bioavailability. However, many factors governs the drug delivery from transdermal patch. This reviews give insights for factor governing drug permeation and excipients needed in casting a transdermal patch.

Keywords: Transdermal; Patch; Bioavailability; Drug permeation

Abbreviations: TDDS: Transdermal Drug Delivery System; DMSO: Dimethyl Sulfoxide; PSA: Pressure Sensitive Adhesives; OTC: Over The Counter; LPP: Lipid-Protein Partitioning

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