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Advancements in Civil Engineering & Technology

A Brief Review of Pathogenesis of Endometriosis

Submission: November 02, 2020; Published: December 01, 2020

Volume2 Issue1 December, 2020


Endometriosis is an estrogen-dependent benign inflammatory disease, which is characterized by presence of endometrial-type mucosa in extra-uterine sites and causes chronic inflammatory at the site of lesion [1,2]. This disease affects their quality of life, work efficiency and sexual life [3] and cause of 25-70% of severe pelvic pain, dysmenorrhea, dyspareunia and infertility [4]. the proposed pathogenic theories are including retrograde menstruation, coelomic metaplasia, induction theory [5]. According to the most covincing modle, the retrograde menstruation phenomenon is accepted theory and states that viable endometrial fragments reaching the peritoneal cavity. they can implant, grow and invade onto the peritoneum and abdominal organ, proliferate and cause chronic inflammation with formation of adhesions [6].

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