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Abstract

Advancements in Civil Engineering & Technology

Elevated Serum Delta Bilirubin Might Predict the Occurrence of Different Types of Jaundice with Special Reference to Chronicity of the Disease

Submission: February 20, 2020; Published: March 4, 2020

Volume2 Issue1 March, 2020

Abstract

Background: Present study was aimed to evaluate whether measurement of serum delta bilirubin and albumin level predict the chronicity and subsequent impaired hepatic function across the spectrum of different types of jaundice.

Methods: Serum total bilirubin, Delta bilirubin, albumin and GGT activity was measured by reflectance spectrophotometry.

Result: Decreased serum albumin was found in a significant inverse correlation with elevated delta bilirubin level among the subjects with obstructive (r=-0.4217, p=0.0023) and hepatic jaundice (r=-0.4214, p=0.0023).

Conclusion: Significant inverse relationship between elevated delta bilirubin and lower albumin level might indicate that the chronicity of the disease may be the predominant factor in hepatobiliary obstruction or hepatocellular injury that may worsen the pathology of obstructive or hepatic jaundice.

Keywords: Delta bilirubin; Albumin; Obstructive jaundice; Hepatic jaundice; Total bilirubin

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