Abstract

COJ Technical & Scientific Research

Significance of Functional Group in Indole Molecule: Toward Sensitivity of Biosensor

  • Open or CloseZaved Hossain Khan*

    Jashore Science and Technology University, Bangladesh

    *Corresponding author: Zaved Hossain Khan, Jashore Science and Technology University, Jashore, Bangladesh

Submission: January 03, 2020; Published: January 22, 2020

Abstract

In this opinion, I focus my attentions on the effect of the functional group in indole molecules onto their potential response with disuccinimidyl suberate (DSS) modified indium tin oxide (ITO) electrode. It was aimed to discuss the variation of potential response of self-assembled monolayer modified ITO electrode for various molecules containing indole ring. A great response with different sensitivity was demonstrated to achieve a linear relationship with the different analyte concentration. However, the magnitude of the potential shift was found to depend on the molecular structure. From a fundamental viewpoint, it seems that interest is based not only on high sensitivity but also on the effect of the functional group substituted onto the indole ring.

Keywords: Modified electrode; Potential response; Sensitivity; Biomolecules; Functional group

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