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Associative Journal of Health Sciences

Regenerative Endodontics of Necrotic Immature Permanent Teeth: Scientific Integrity Review

  • Open or CloseAna Carolina Neckel1, Júlia Vitali Dondossola1, Patrícia Maria Poli Kopper2, Josiane de Almeida3, Renan Antônio Ceretta4 and Anarela Vassen Bernardi4*

    1Departamento Ciências da Saúde, Curso de Odontologia, Universidade do Extremo Sul Catarinense, Santa Catarina, Brasil

    2Departamento de Odontologia Conservadora, Curso de Pós-graduação em Odontologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brasil

    3Departamento de Ciências da Saúde, Curso de Odontologia, Disicplina de Endodontia, Universidade do Sul de Santa Catarina, Santa Catarina, Brasil

    4Departamento de Ciências da Saúde, Curso de Odontologia, Universidade do Extremo Sul de Santa Catarina, Santa Catarina, Brasil

    *Corresponding author: Anarela Vassen Bernardi, Department of Health Sciences,Dentistry Course, Universidade do Extremo Sul de Santa Catarina, Santa Catarina, Brazil

Submission: August 30, 2022;Published: September 13, 2022


The aim of this study was to identify a clinical protocol on regenerative endodontics based on scientific evidence for necrotic immature permanent teeth, as well as to conduct a critical evaluation of the results for modifying the clinical protocol of the Dentistry undergraduate course at the Universidade do Extremo Sul Catarinense (UNESC). The research is a qualitative, retrospective, descriptive and documental typified as literature review. The research was conducted using the following databases: PubMed and Latin American Literature and from the Caribbean on Health Sciences (Lilacs), using a combination of the following terms: Regenerative Endodontics OR Immature Tooth AND MTA. The research was concluded on 21 March 2021. The inclusion criteria were presence of the keywords, English language, publication years from 2015 to 2021 and dentistry journals with an impact factor higher than 0.001. The exclusion criteria were articles that were repeated between the databases, abstracts that did not present the researched topic and articles without available abstracts. Eleven articles have been identified and several protocols for regenerative endodontic treatment. It is concluded that the literature presents relevant requirements that provide reflections for the change of the traditional protocol hitherto performed at UNESC. Regenerative endodontics is an alternative treatment for necrotic immature teeth.

Keywords:Regenerative endodontics; Dental pulp necrosis; Stem cells

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