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Advancements in Case Studies

A Clinical Challenge: A Rare Case of Neoadjuvant Chemotherapy for Stage IB3 Cervical Cancer in Pregnancy

Submission:December 18, 2020; Published: December 23, 2020

DOI: 10.31031/AICS.2020.03.000551

ISSN 2639-0531
Volume3 Issue1


Treatment of cervical cancer during pregnancy (CCP) is controversial and individual. Here, we present a successful case of a 31-year-old woman who was diagnosed of stage IB3 cervical squamous cell carcinoma at her 14th week of pregnancy. As the patient had a strong desire to preserve her pregnancy, she was first treated with 4 cycles of neoadjuvant chemotherapy (NACT), cisplatin 75mg/m2 and paclitaxel 175mg/m2 per 21 days. Then a cesarean section followed by a radical hysterectomy and pelvic lymphadenectomy was performed at her 36 weeks and 3 days of gestation, and no post operational adjuvant therapy was performed. With a follow-up for 12 months post operation, the neonate and the mother showed no complications related to the treatments and there was no recurrence of the patient during follow-up.

Keywords: Neoadjuvant chemotherapy, Cervical cancer, Pregnancy

Abbreviations: CC: Cervical Cancer; CCP: Cervical Cancer during Pregnancy; NACT: Neoadjuvant Chemotherapy; SCC: Squamous Cell Carcinoma

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