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Abstract

Advancements in Case Studies

The Role of Blood Microbiome and Microbial Product Translocation in Disease Pathogenesis

  • Open or CloseXiaochun Li1, Wenwen He2, Yifang Wen3, Wei Jiang4,5 and Lei Huang6*

    1The Sixth People’s Hospital of Xinjiang, Antiviral Treatment Center for HIV/AIDS, China

    2The Sixth People’s Hospital of Xinjiang, Clinical Laboratory Center, the Sixth People’s hospital, China

    3The Sixth People’s Hospital of Xinjiang, Hepatitis Treatment Center, China

    4Department of Microbiology and Immunology, Medical University of South Carolina, USA

    5Divison of Infectious Diseases, Department of Medicine, USA

    6The 302 Hospital of PLA, Treatment and Research Center for Infectious Diseases, China

    *Corresponding author: Lei Huang, The 302 Hospital of PLA, Treatment and Research Center for Infectious Diseases, China

Submission:November 09, 2020; Published: November 20, 2020

DOI: 10.31031/AICS.2020.02.000548

ISSN 2639-0531
Volume2 Issue5

Abstract

Circulation has been considered in a sterile condition in individuals without live microbial infections. However, recent publications from our group and others highlight detection of blood microbiome or microbial molecules in healthy individuals and individuals with various diseases, as well as their potential roles in disease pathogenesis. In this review, we introduce the published studies and research advancement in the field of blood microbial and microbial translocation in disease immunopathogenesis.

Keywords: Blood microbiome; Microbial product translocation; Disease pathogenesis

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