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Advancements in Case Studies

B-cell Lymphoma as a Complication of Sjogren’s Syndrome: A Case Report

Submission:January 21, 2020; Published: February 11, 2020

DOI: 10.31031/AICS.2020.02.000539

ISSN 2639-0531
Volume2 Issue3


Sjogren’s Syndrome is an autoimmune dysfunction of the exocrine glands that causes dryness of the eyes, mouth, skin. One of its worst complications is MALT lymphoma, which is caused by deregulation of B-cell proliferation. In this case report a female patient with primary Sjogren’s Syndrome presents a parotid swelling, concluded by biopsy that was a lymphoma. After resection, she was treated with rituximab. The immunotherapy caused the remission of the lymphoma and the symptoms of the primary disease. The use of immunotherapy might be an alternative to the traditional immunosuppressants used for Sjogren’s Syndromea.

Keywords: Sjogren’s syndrome; Sicca syndrome; B-cell lymphoma; Rituximab; Case report

Abbreviations: SS: Sjogren’s Syndrome; PET Scan: Positron Emission Tomography

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