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Non-genetically Editing Dysbiotic Microbiome Using Probiotic-specific Prebiotics for Treatments of Human Skin Diseases

  • Open or CloseHuang RY1,2, Raymond Herr D3, Huang CM4 and Jiang Y5*

    1Department of Mechanical and Aerospace Engineering, USA

    2Canyon Crest Academy, USA

    3Department of Pharmacology, Singapore

    4Department of Biomedical Sciences and Engineering, Taiwan

    5America Diagnosis, Inc., USA

    *Corresponding author:Jiang Y, America Diagnosis, Inc., USA

Submission:January 28, 2020; Published: February 04, 2020

DOI: 10.31031/AICS.2020.02.000538

ISSN 2639-0531
Volume2 Issue3


External interruption in the balance of microbes in the microbiome can lead to a dysbiotic microbiome which has been linked to a variety of human diseases. Antibiotics have been widely used for treatments of infectious diseases in humans, but they are generally not pathogen specific and run a risk of yielding antibiotic-resistant microbes. Inappropriate use of antibiotics may disrupt the homeostasis of human microbiome, causing dysbiotic microbiome and abolishing natural and self-curative of human body. Here, we review a new approach by using bacterial specific prebiotics to amplify the fermentation activity of probiotic bacteria against pathogens and keep the microbiome balanced for optimal health. The pros and cons of using skin prebiotic as a new modality for improvement of skin health are compared to other treatments including antibiotics, vaccines, bacteriophages, genetically modified/engineering bacteria and live skin probiotic bacteria.

Keywords:Dysbiotic; Prebiotic; Probiotic; Microbiome; Skin

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