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Advancements in Case Studies

Idiopathic Necrotizing Granulomas of the Thyroid: Report of a Rare Case

  • Open or Close Anupam K1, 2, Jason DE2, Diva RS3 and Vahab F1, 2*

    1Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, USA

    1Department of Medicine, Mayo Clinic, Rochester, USA

    1Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, USAa

    *Corresponding author: Vahab Fatourechi, MD, Professor of Medicine, Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Department of Medicine, Mayo Clinic, 200 First Street SW, Rochester, New York, USA, MN 55905

Submission: February 14, 2018; Published: May 18, 2018

DOI: 10.31031/AICS.2018.01.000510

ISSN 2639-0531
Volume1 Issue2


Granulomatous disease of the thyroid commonly presents as sub acute (De Quervain) thyroiditis [1]. Necrotizing granulomas in thyroid have been reported with infection (tuberculous [2] and fungal [3]), granulomatosis with polyangiitis [4], plasma cell granuloma[5], post-surgical/palpation thyroiditis [6] and rarely in sarcoidosis (usually causes non-necrotizing granulomas). We present a case of necrotizing granulomas within thyroid of unclear etiology associated with sudden profound hypothyroidism.

Keywords: Necrotizing granulomas; Hypothyroidism; Tuberculosis; Subacute thyroiditis

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