Definition

Glucopuncture is an injection-based therapy for the management of musculoskeletal conditions. It consists of multiple local injections with glucose or dextrose in low concentrations. These injections of G5W (Glucose 5% in Water) or D5W (Dextrose 5% in Water) seem to have a favorable effect on the repair mechanisms of damaged or inflamed tissues such as muscles, tendons, ligaments, cartilage, and peripheral nerves. The exact mechanism of action is not well understood and is likely multifactorial. Large randomized controlled trials are warranted to make specific recommendations regarding ideal protocols and indications. The introduction of a new term to describe these injections might give more exposure to its possible benefits among both patients and professional health care providers.

Keywords:Glucopuncture; Injection; Dextrose; Protocols; TRPV1 receptor; Scar tissue; Osteoarthritis; Glucose; Prolotherapy; Aerobic respiration; Cell metabolism; ATP-based theory; Primary sensory axons; Neurogenic inflammation; Chronic rotator