Abstract

Cholangiocarcinoma is a malignant neoplasm originated in the bile ducts or gallbladder. It is considered quite aggressive and usually metastasizes for regional lymph nodes and lungs. The treatment is by surgical resection and chemotherapy, which are very invasive and aggressive methods. Viscum album (VA) extract has immunomodulatory and cytotoxic properties capable of acting directly on the tumor and its microenvironment, as well as in other systems. Viscum album improves the quality of life as it does not present significant side effects compared to the traditional allopathic treatment. A case of Cholangiocarcinoma in a dog with pulmonary and splenic metastasis is reported in the present study. The patient was treated by subcutaneous and intravenous administration of ultra-diluted Viscum album for 11 months. The Viscum album administration improved the quality of life of the animal and decreased the tumor growth speed.

Keywords: Tumor; Quality of life; Metastasis