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Advancements in Bioequivalence & Bioavailability

Frequency of Anemia and Possible Risk Factors Among Sudanese Children with End Stage Renal Disease

Submission: September 25, 2018; Published: November 13, 2018

DOI: 10.31031/ABB.2018.02.000527

ISSN 2640-9275
Volume2 Issue1


Background: Anemia is a common Feature of chronic kidney disease, but the management of anemia in children is complex. Erythropoietin and Supplemental iron are used to maintain hemoglobin levels. The aim of this study to determine the Frequency of anemia and possible Risk Factors Among children with End stage renal disease.

Methods: A total of 96 children, 61males (63.5%) and 35 Females (36.5%), were attended at hemodialysis units in Khartoum state were enrolled in the study and Frequency of anemia was estimated by analyzing CBC on blood counter (sysmex). The concentration of iron profile, C-reactive protein and parathyroid hormone was measured using COBAS INTEGRA 400 PLUS and COBAS E411.

Results: 99% of children were anemic, 4.17% of them were suffering from iron deficiency anemia and there are other causes contributing to anemia in ESRD patients which are inflammation and hyperparathyroidism.

Conclusion: The prevalence of anemia in children on hemodialysis in Sudan appears to be higher than that reported in other studies despite extensive use of rHuEPO and iron supplementation.

Keywords:Hemodialysis; Anemia; Erythropoietin; Hemoglobin; Iron; Parathyroid hormone; Children; Khartoum; Sudan

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