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Advancements in Bioequivalence & Bioavailability

Bioinformatics Programming for Bioavailability Analysis of Sequence Patterns in Public Genomic Databases

  • Open or Close Changsu Dong1, Roy Lee1, Joseph Sayad2, and Konstantinos Krampis3*

    1Department of Biological Sciences, Weill Cornell Medical College and Hunter College, USA

    2Department of Biological Sciences, Hunter College, USA

    3Department of Physiology and Biophysics, Cornell University, USA

    *Corresponding author: Konstantinos Krampis, Department of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Cornell Medical College, Cornell University, New York, USA

Submission: April 19, 2018; Published: May 10, 2018

DOI: 10.31031/ABB.2018.01.000508

ISSN 2640-9275
Volume1 Issue2


In this study we present a novel bioinformatics software for the analysis of bioavailability of short amino acid peptides, in various proteins found across four phylogenetic kingdoms of Archaea, Bacteria, Mammals and Plants. In order to assess bioavailability of these peptides, we have used a set of large-scale protein databases from the National Center for Biotechnology Information, and the Basic Local Alignment Search Tools (BLAST+) search program. In our results we present the counts of peptides matches across the phylogenetic kingdoms, and also in further detail for Gram positive or negative bacteria. Our bioinformatics software is written in Python and is made available within this publication as freely available for academic and non-profit use.

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