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Abstract
Research in Pediatrics & Neonatology
Derangements of Sodium Homeostasis in Acute Infantile Diarrhea
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Open or Close Ismail E Haffejee*
Department of Paediatrics and Child Health, University of KwaZuluNatal, South Africa
*Corresponding author: Ismail E Haffejee, MBBCh, FCP(Paed), MD, FCFP(SA), Honorary Professor and Sessional Consultant, Department of Paediatrics and Child Health, Nelson R Mandela School of Medicine, University of KwaZuluNatal, Durban, South Africa
Submission: October 06, 2017; Published: May 09, 2018
ISSN : 2576-9200Volume2 Issue1
Abstract
The majority of infants with acute diarrhea have isonatraemic dehydration, where the serum sodium (Na) concentration is within the normal range of 135 to 150 mEq/L. They respond well to both oral and intravenous (IV) rehydration, the latter usually as halfstrength Darrow’s solution which has a Na concentration of 65 mEq/L. Intravenous solutions with higher osmolalities such as Ringer lactate, half-normal saline or even normal saline can safely be used to treat infants showing signs of severe dehydration with or without shock. Clinical signs of dehydration will not be discussed in this paper.
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