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Abstract
Research & Investigations in Sports Medicine
Brain Derived Neurotrophic Factor and Exercise
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Open or Close Daniel Jaffe*, Jennifer Hewit, Kelly Hamilton, Jessica Burkett, Josiah Luce and Alexander Bedard
1Department of Physical Education, United States Military Academy, USA
*Corresponding author: Daniel Jaffe, Department of Physical Education, United States Military Academy, West Point, 10996, NY, USA
Submission: February 26, 2018; Published: March 28, 2018
ISSN: 2577-1914Volume2 Issue3
Abstract
Brain-derived neurotrophic factor (BDNF), a dimeric protein found throughout the brain, promotes the survival of nerve cells by playing a role in the growth, maturation, and maintenance of cells [1]. Along with supporting the survival of existing neurons, BDNF encourages differentiation and growth of new neurons and synapses [2,3]. In the brain the hippocampus, cortex, and basal forebrain, which are vital to learning, memory, and higher thinking, are all locations where BDNF is active [4]. A number of stimuli have been found to increase BDNF gene regulation including light in the visual cortex, osmotic in the hypothalamus, electrical in the hippocampus, and exercise in the hippocampus [5].
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