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Abstract

Perceptions in Reproductive Medicine

Clinical Applications of the Test on Acrosin Activity

  • open or closeShuai Zhang1,†, Mengyuan Lin2,†, Xiaowei Nie3, Lisha Tang1, Huaiyun Tang1* and Shi-Wen Jiang4*

    1Clinical Center of Reproductive Medicine, Lianyungang Maternal and Child Health Hospital, Lianyungang, China. senomega@hotmail.com

    2Center of Reproductive Medicine, Women’s Hospital of Jiangnan University, Wuxi Jiangsu, 214002, China

    3Department of Reproductive Medicine, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China

    4Lianyungang Research Institute for Women’s and Children’s Health, Lianyungang Maternal and Child Health Hospital, Lianyungang, Jiangsu, China

    †These authors contributed equally

    *Corresponding author:Huaiyun Tang, Clinical Center of Reproductive Medicine, Lianyungang Maternal and Child Health Hospital, Lianyungang, China. E-mail: thylyg@163.com

Submission: October 12, 2023;Published: November 06, 2023

Volume6 Issue1
November , 2023

The acrosin activity is assayed by many reproductive medicine centers as an indicator of sperm cell functions. The result of this test is often applied for assessing the quality of spermatozoa and risk of male infertility; for the measurement of sperm cell viability in research and/or optimization of sperm cryopreservation in different species; for decision making on ICSI procedure in IVF. This minireview summarizes the detection method, the relation between acrosin activity and sperm cell morphology/ function and discusses the applications of acrosin activity for research and clinical purposes. Comments on the knowledge gaps and future studies are also provided.

Keywords:Acrosin activity; Acrosome; Male infertility; ICSI

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