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Perceptions in Reproductive Medicine

Predictors of Ovarian Reserve and Ovarian Stimulation Outcome in Infertile Women

  • Open or Close Juliano Brum Scheffer*

    Brazilian Institute of Assisted Reproduction, Belo Horizonte, Brazil

    *Corresponding author: Juliano Brum Scheffer, Scientific Director of Ibrra, Brazilian Institute of Assisted Reproduction, Belo Horizonte, Brazil

Submission: December 04, 2017;Published: December 08, 2017

DOI: 10.31031/PRM.2017.01.000510

ISSN: 2640-9666
Volume1 Issue2


The fecundity of women begins to decrease after the age of 30 years, primarily as a result of a decrease in the proportion of normal eggs available, which in turn is a consequence of a continuous process of oocyte atresia. Although all women experience this decrease in fecundity, it is difficult to predict the pace of reproductive decline in an individual woman. This age-related decline in fecundity is characterized by a decrease in both egg quality and number, and a population-based change in the expression of markers of ovarian activity, such as a gradual increase in circulating FSH and decreases in circulating anti-Müllerian hormone (AMH) and inhibin B concentrations.

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