Orthoplastic Surgery & Orthopedic Care International Journal

Title of the Article: A Rare Case Report of Diffuse Large B- Cell Lymphoma of Bone with Multicentric Involvement

  • Open or Close Naveen Mittal*

    Department of orthopaedics, Government Medical College Hospital, India

    *Corresponding author: Naveen Mittal, Department of orthopaedics, Government Medical College Hospital, Sector-32, Chandigarh, India

Submission: February 07, 2018; Published: March 14, 2018

DOI: 10.31031/OOIJ.2018.01.000516

ISSN: 2578-0069
Volume1 Issue4


Primary bone lymphomas (PBL) are rare, even though secondary involvement of the bone marrow is a common event in systemic lymphomas. Most PBL are Primary Bone Diffuse Large B-Cell Lymphomas (PBDLBCL). In the present case report, a 58 year female presented with long term pain in the left thigh along with palpable subcutaneous masses in the head. The MRI done in the periphery reported it as a cystic lesion and was advised extended curettage. We reviewed the case and carried out CT pelvis with left thigh and CT head to see for bony involvement which showed involvement of the sacrum, femur and parietal bones. The lesions were biopsied subjected to histopathology and immunohistochemistry which confirmed the diagnosis .The patient is presently on CHOP regime highlighting the large frequency with which such cases are misdiagnosed leading to progression of the disease.

Keywords: Primary bone diffuse large B-cell lymphoma (PBDLBCL); Misdiagnosis; Immuno histo chemistry; CHOP regime

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