Abstract

Poly glycerol sebacate (PGS) is a synthetic polymer widely known in the field of tissue engineering and has achieved remarkable attention due to its desired properties such as having surface degradation and elastomeric behavior. Different synthesis methods based on pre-poly condensation step and crosslinking have been defined for PGS production till now. Thanks to its physico-chemical, mechanical, thermal and morphological properties; it has been proposed for numerous tissue engineering applications ranging from soft to hard tissue by researchers. Both in-vitro and in-vivo many research studies have been carried out not only upon PGS but also its composite forms. In addition, different production techniques and characterization methods have been pursued. Within the scope of this mini review article; the importance of PGS along with its discovery, production techniques, characterization and applications were described and explained.