Abstract

We present a review of the results of research to identify olfactory receptor gene sequences from the Human Genome. This effort began soon after the publication of the first draft of the genome. Subsequent publications of the genome have allowed the evolution of OR gene identification with improved accuracy. We performed a comprehensive sequence analysis to identify 100% sequence matches, as well as partial matches by performing the same sequence matching step against random partial regions of sequences. Only sequences supplied to us from the groups that mined the olfactory receptor sequences from the genome or were available online were used in the analysis. The results are publicly available at https:// ordb.biotech.ttu.edu/ORDB/info/humanorseqanal. We also performed a similar assessment of mouse olfactory receptor sequences from two groups that assessed the mouse genome, publicly available at https://ordb.biotech.ttu.edu/ORDB/info/mouseorseqanal. Both resources are linked through a list of potential orthologs between the two species’ receptor sequences. This review also contains a discussion of nomenclatures of these genes and the resources as information dissemination portals.