1The North Cap University, India
2IIT Delhi , India
*Corresponding author: Geetika Munjal, The North Cap University, Madasu hanmandlu, Gurugram, Delhi, India
Submission: December 16, 2017; Published: February 06, 2018
ISSN: 2578-0247Volume1 Issue1
The phylogenetic tree portrays a relationship between sets of species and represents a model of molecular evolution. The current forms of species retain many of their ancestral features, some of which gradually change to help these species adjust to their environment. We provide a review of phylogenetic construction and validation methods and its application in cancer analysis. The need of alignment free methods for sequence comparison is also explored as an alternative to alignment based methods.
Keywords: Phylogenetics; Sequence comparison; Tree validation; Alignment free methods
Abbreviations: DNA: Deoxyribonucleic Acid; RNA: Ribonucleic Acid; MAST: Maximum Agreement Subtree