Abstract

The article reports on a study devoted to the clinical and laboratory characteristics of the immune-metabolic stress in purulent-inflammatory diseases of the skin and soft tissues. The study included findings in 85 patients with 4 types of mono- and combined purulent-inflammatory diseases of the skin and soft tissues. Diagnostic changes were established in general indicators, detailed to the individual links of immunity, as well as the primary and secondary metabolic parameters of free radical oxidation of lipids, proteins, enzymatic and non-enzymatic mechanisms of the antioxidant system with the formalization of supporting indicators in diagnostic formulas. A direct and inverse correlation has been revealed between the key immune-metabolic indicators of patients, indicating the functional unity of the factors of immune-oxidant stress. The reference comparison group consisted of 30 single donors.

Keywords:Immune-metabolic stress; Purulent-inflammatory diseases; Skin and soft tissues; Immunologic parameters; Metabolic parameters