Abstract

(COVID-19) Corona virus towards the end of 2019, an invisible virus pneumonia outbreak occurred in Wuhan (Hubei, China) due to an unknown reason caused by the severe acute respiratory syndrome coronavirus. The virus is expressed in the form of a series of virus’s pneumonia (COVID-19). In January 2020, it was first appeared in human body in the form of severe acute respiratory syndrome coronavirus (SARS-CoV), then in the Middle East in the form of respiratory syndrome coronavirus (MERS-CoV) and in the outer population as (SARS-CoV-2). On February 11, 2020, the Honorable Director General of the World Health Organization (WHO) Dr. Tedros Adhanom Ghebreyesus SARS-CoV-2 named the disease “COVID-19”. The situation was later declared the pandemic by the WHO on March 20, 2020, when the number of affected countries exceeded a hundred, with more than 100,000 cases detected and more than 4,000 deaths. Corona virus disease 2019 (COVID-19) is an RNA virus and together with a regular crownlike appearance as it lies under an electron microscope whose cover corresponds to the emergence of glycoprotein spikes. The corona virus has now become an epidemic worldwide. It has spread all over the world, started first in China, then in Arabia, Italy, Spain, the United States and Bangladesh. Every moment of which seems to be singing the slogan of death and the number of deaths is increasing. In this review, we provide a brief introduction to the general characteristics of SARS-CoV-2 and discuss current knowledge of immune pathogenesis based on current perceptions of SARS-CoV and MERS-CoV infections, diagnosis, prevention and treatment of SOVID-19, which may be helpful in offering novel insights and potential therapeutic targets for fighting against the SARS-CoV-2 infection.

Keywords: Immunity; Survival; Covid-19