Abstract

Drug discovery is a process by which new drug molecules are discovered. Despite of advances in technology and understanding of biological systems, drug discovery is still a lengthy, expensive, difficult, and inefficient process with low rate of new therapeutic discovery so there is always needed to search for better drugs no matter how well the existing ones serve. Molecular modification is a revolution in contemporary drug development and still a major line of approach for the discovery of new drugs. Any alteration in the structure of known and previously characterized molecule for the purpose of enhancing its usefulness as drug is called as Molecular modification. The review article presents the significance of molecular modification and might be helpful in the development of the novel lead molecules to potential drug candidates for future.

Keywords: Drug discovery; Drug development; Better drugs; Molecular modification