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Innovation in Tissue Engineering & Regenerative Medicine

Advances and Innovations and Impediments in Tissue Engineering and Regenerative Medicine

  • Open or CloseShivaji Kashte1 and Sachin Kadam1,2

    1 Center for Interdisciplinary Research, D. Y. Patil University, India

    2 Advancells, India

    *Corresponding author:Sachin Kadam, Advancells: A Unit of Saffron Naturale Product Pvt. Ltd., India

Submission: April 08, 2019; Published: May 07, 2018

DOI: 10.31031/ITERM.2019.01.000510

ISSN: 2578-0336
Volume1 Issue2


The evolving arena of regenerative medicine requires the use of cells, scaffolds, tissues or genetically edited elements as therapeutic agents for implantable engineered tissues and organs that can regenerate physiological functions. A variety of fabrication techniques like gas foaming, phase separation, salt leaching, and freeze drying have been developed that successfully regenerate complex and functional tissues. Recently developed three-dimensional (3D) printing technology promises to bridge the differences between artificially engineered tissues and native tissues. After 3D printing, 3D bioprinting was introduced as an ultimate solution for vascularized tissue fabrication. The large number of tissues such as bone, cartilage, skin, myocardial, kidney, liver, and lung tissue models were investigated with 3D bioprinting. As there is a need for stimulus-responsive geometry, four-dimensional (4D) printing technology has been developed to fabricate structures that can transform their shape. Tissue engineering and regenerative medicine providing exciting results has brought a new era of medical research and applications with value addition in the field of medicine. It will be important to ensure that appropriate technologies are developed, validated that could result to the betterment of human situation. The positive role of regulatory authorities could enhance the morale of the researchers and scientific communities. This could translate in to the lifesaving new innovations.

Keywords: Tissue engineering and regenerative medicine; Three-dimensional (3D) printing; 3D bioprinting; Four-dimensional (4D) printing

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