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Abstract
Interventions in Obesity & Diabetes
Potential Clue Towards the Association of Fish Intake/PPARGC1A Gene/Immune Status Among Non-Obesity-Family-History Overweight Youth: A Case Report and Update from a Prospective Study
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Open or CloseJuan Xie1, Fei Wu2, Yongmei Li3, Bei Sun4, Xinyue Zhi1, Xin Zhang5* and Qing
Gu6*
1Department of Epidemiology and Biostatistics, School of Public Health, and Tianjin Key Laboratory of Environment, Nutrition & Public Health,Tianjin Medical University, Tianjin, China
2School of Public Health, Tianjin Medical University, Tianjin, China
3Department of Pathogen Biology, School of Basic Medical Sciences, Key Lab of Immune Microenvironment and Disease (Ministry of Education) Tianjin Medical University, Tianjin, China
4NHC Key Laboratory of Hormones and Development(Tianjin Medical University), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Medical University Chu Hsien-I Memorial Hospital and Tianjin Institute of Endocrinology, Tianjin, China
5Department of Maternal, Child and Adolescent Health, School of Public Health, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China
6Tianjin Centers for Disease Control and Prevention, Tianjin, China
*Corresponding author:Xin Zhang, Department of Maternal, Child and Adolescent Health, School of Public Health, School of Basic Medical Sciences, Tianjin, China
Submission: February 05, 2020Published: February 12, 2020
ISSN : 2578-0263Volume3 Issue3
Abstract
We have already known that lipid metabolism homeostasis existed in children and adolescents would be associated with PPARGC1A methylation status then impact the onset or progress of many chronic diseases in adulthood. And fish intake could show impact on the mRNA and methylation for many genes, thus help to control lots of diseases. This case highlighted more fish intake might be involved in down regulating PPARGC1A methylation and help to correct overweight, also do good to improve immune status among youth.
Keywords: Dietary factor; PPARGC1A gene; Immune status; Overweight; Adolescent
Abbreviations: PPARGC1A: Peroxisome Proliferative Activated Receptor Gamma Coactivator 1A; CAMP: Cyclic Adenosine Monophosphate
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