Abstract

Purpose: This study aimed to review the need for identification and surveillance of Premalignant Gastric Lesions (PGLs), which have potential implications for clinical practice and public health in terms of Gastric Cancer (GC) prevention and mortality reduction in low-incidence areas.
Methods: We conducted a narrative review of the latest literature.
Results: We discuss the benefit of a prevention strategy for GC by applying screening for PGLs in patients aged > 45 years or even in younger populations.
Conclusion: Few data are available on the endoscopic assessment and surveillance of PGLs, although international guidelines recommend the surveillance of such precancerous lesions. Scientists must conduct further prospective studies, collect more national data about the cost-effectiveness of such screening, and provide crucial insights into PGLs progression to GC.

Keywords: Premalignant gastric lesions; Surveillance; Identification; Epidemiology; Gastric cancer prevention