Abstract

The Gallbladder neoplasia is rare and has a high mortality rate, thus surgery is still the usual curative treatment for the disease. Once its diagnosis is usually tricky and at a late stage, there is the necessity of using neoadjuvant chemotherapy in advanced cases. We report the case of a 51-year-old man diagnosed with gallbladder cancer presenting liver invasion but no metastasis. Initially, it was considered inoperable so the patient was submitted to neoadjuvant chemotherapy with gemcitabine. By the end of chemotherapy, the radiological examination showed the complete reduction of the lesion, choosing to proceed with the salvage surgery. Therefore, it was performed conventional cholecystectomy with liver resection (segments V and VI) and regional lymphadenectomy. The histopathological examination did not show neoplasia in any of the resected tissues or lymph nodes involvement. The patient evolved to the cure of the disease with chemotherapy treatment. Six years after the primary diagnosis, the patient remains being monitored with no recurrence of the tumor.