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Global Journal of Endocrinological Metabolism

The Role of Diet Therapy in the Patients treatment with Hyperuricemia and Metabolic Syndrome
  • Open or Close Gapparova KM1* and Yu G Chekhonina1,2

    1Federal Research Centre of Nutrition, Biotechnology and Food Safety, Russia

    2NI Pirogov Russian National Research Medical University, Russia

    *Corresponding author: Gapparova KM, Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russian Federation, Russia

Submission: March 23, 2018; Published: April 19, 2018

DOI: 10.31031/GJEM.2018.01.000525

ISSN 2637-8019
Volume1 Issue5


There is no doubt about the importance of the amount of protein in the diet of obese patients. Adequate protein content in the hypo-caloric diet helps maintain muscle mass and reduce hunger. At the same time, the most common comorbid condition in obesity is hyperuricemia. At present, according to the results of numerous studies, hyperuricemia (GI) can really be considered as an independent risk factor for cardiovascular complications; it is directly related to other metabolic risk factors and is an important component of metabolic syndrome. In general, the correlation analysis demonstrates that the uric acid values correlate with almost all metabolic syndrome components, which may indicate the pathogenic role of uric acid in the development of this metabolic disorder [1-3]. According with the foregoing, the issue of not only quantitative but also qualitative composition of protein in the diet, as purine-containing products, which in turn affects the fluctuations in the level of uric acid in the blood serum, is topical. In addition, in the process of reducing body weight in patients with obesity, especially morbid, there is often an increase in the level of uric acid, which is the result of active catabolism of muscle mass. All this is a prerequisite for creating modified diets for patients with metabolic syndrome including hyperuricemia.

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