Department Department of Biotechnology, Baghdad University, Iraq
*Corresponding author: AL Azzawie HF, Department Department of Biotechnology, Baghdad University, Iraq
Submission: August 28, 2017; Published: November 13, 2017
ISSN 2637-8019Volume1 Issue2
Recurrent miscarriage (RM), defined as three or more consecutive pregnancy losses before 20 weeks of gestation, affects approximately 1-5% of pregnant women . The etiology of RM is still unclear. Among the large number of miscarriage-related factors, are uterine structural defaults, defective ploidy control of the embryo, defective immunological dialog between the embryo (or the fetus) and the uterus sometimes in relation with immunological disorders (such as autoimmune diseases), thrombophilia, and free radical metabolism imbalance . Numerous studies attempted to correlate variants of genes supposed to be intervening in the different facets of the early maternal–fetal or maternal embryonic dialog, and eventually modify the outcome of fertilization, leading to success or failure of post implantation’ development.