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Abstract
Gerontology & Geriatrics Studies
Homozygous Long-Lived Ames Dwarf Mice
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Open or CloseIsao Eto*
University of Alabama at Birmingham, USA
*Corresponding author: Isao Eto, University of Alabama at Birmingham, USA
Submission: November 16, 2021;Published: December 03, 2021
ISSN 2578-0093Volume 7 Issue 3
Abstract
Homozygous long-lived Ames dwarf mice display two different physiological characteristics. On one hand, they are pretty “resistant to cancer” relative to their wildtype or heterozygous siblings. On the other and, they are also “long-lived” relative again to their wild-type or heterozygous siblings. The most simplistic explanation of the existence of these two different characteristics in the homozygous long-lived Ames dwarf mice could be that the “cancer-resistant” characteristics cause the “long-lived” characteristics of these mice. However, this explanation is only statistical with no cause-and-effect biochemical or molecular biological mechanisms.
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