Crimson Publishers Publish With Us Reprints e-Books Video articles


Gerontology & Geriatrics Studies

Homozygous Long-Lived Ames Dwarf Mice

  • Open or CloseIsao Eto*

    University of Alabama at Birmingham, USA

    *Corresponding author: Isao Eto, University of Alabama at Birmingham, USA

Submission: November 16, 2021;Published: December 03, 2021

DOI: 10.31031/GGS.2021.07.000663

ISSN 2578-0093
Volume 7 Issue 3


Homozygous long-lived Ames dwarf mice display two different physiological characteristics. On one hand, they are pretty “resistant to cancer” relative to their wildtype or heterozygous siblings. On the other and, they are also “long-lived” relative again to their wild-type or heterozygous siblings. The most simplistic explanation of the existence of these two different characteristics in the homozygous long-lived Ames dwarf mice could be that the “cancer-resistant” characteristics cause the “long-lived” characteristics of these mice. However, this explanation is only statistical with no cause-and-effect biochemical or molecular biological mechanisms.

Get access to the full text of this article